The most urgent warning signs that require calling 911 immediately include: vomiting blood or passing black, tarry, or bloody stools, which may indicate severe internal bleeding. Sudden confusion, extreme drowsiness, difficulty waking up, or loss of consciousness, which can be signs of hepatic encephalopathy or another medical emergency. Difficulty breathing, severe chest pain, or bluish lips or skin, which require immediate emergency care. Severe or sudden abdominal pain, especially if accompanied by a swollen abdomen, fever, or vomiting. Uncontrolled bleeding from any site that does not stop with pressure. High fever with chills, confusion, or severe weakness, particularly in someone with advanced liver disease, as this may signal a serious infection. A seizure or sudden inability to speak, move, or respond normally. If someone with liver disease experiences any of these symptoms, call 911 immediately or go to the nearest emergency department. Prompt medical attention can be lifesaving.

People living with liver disease should contact their healthcare provider promptly if they notice new or worsening symptoms, even if they are not experiencing an emergency. These symptoms may include: increasing yellowing of the skin or eyes (jaundice). New or worsening swelling in the abdomen, legs, ankles, or feet. Persistent nausea, vomiting, or loss of appetite that makes it difficult to eat or drink. Unexplained fatigue, weakness, or weight loss. Mild confusion, memory problems, or changes in concentration. A fever, signs of infection, or feeling generally unwell. Increased itching, dark urine, or pale-colored stools. Easy bruising or bleeding, or minor bleeding that occurs more often than usual. Difficulty taking medications as prescribed or concerns about side effects. Promptly reporting these symptoms allows healthcare providers to identify potential complications early, adjust treatment if needed, and help prevent more serious health problems. If symptoms become severe.