Can IgA nephropathy be reversed?

 

IgA nephropathy, also called Berger disease, usually cannot be cured or fully reversed. However, it can often be managed and its progression slowed. Some people—especially children—may go into remission. With consistent monitoring and treatment, many people keep working kidneys for decades, and some never develop kidney failure.

An important part of managing IgA nephropathy is controlling factors that can put additional strain on the kidneys. This may include keeping blood pressure in a healthy range, reducing excess sodium, managing diabetes if present, avoiding tobacco, and discussing any over-the-counter medicines or supplements with a healthcare professional. Your nephrologist may recommend regular blood and urine tests to monitor kidney function and protein in the urine, which can help guide treatment decisions over time.

The Liver Hope Foundation (TLHF) provides general education and support for people in Henderson, Nevada, and beyond. We are not a medical provider. Please talk with your nephrologist or healthcare provider about your individual diagnosis and care plan.

 

Frequently asked questions

Clear, practical answers can help you prepare for conversations with your kidney care team. Explore common questions about managing IgA nephropathy, protecting kidney function, and finding support.

Can IgA nephropathy be reversed?

In most cases, IgA nephropathy cannot be fully reversed or cured. Still, the condition can often be managed, and some people experience remission. The goal of care is to reduce kidney inflammation and damage, lower protein in the urine, and protect kidney function over time.

Is there hope if I have IgA nephropathy?

Yes. Many people with IgA nephropathy maintain kidney function for decades, and some never reach kidney failure. Better control of blood pressure and urine protein has improved outcomes, and newer targeted treatments offer additional hope. Your outlook depends on factors such as kidney function, urine protein, blood pressure, and how the disease changes over time.

What treatments may help slow IgA nephropathy?

Healthcare providers often focus on controlling blood pressure and lowering protein in the urine. ACE inhibitors or ARBs are commonly used, and SGLT2 inhibitors may also help protect the kidneys for some people. Ask your nephrologist whether these medicines or newer targeted IgA nephropathy treatments may be appropriate for you.

Why are blood pressure and urine protein important?

High blood pressure and ongoing protein in the urine can increase stress on the kidneys and are linked with faster disease progression. Your nephrologist can explain your personal blood pressure and protein targets and how often they should be checked.

What lifestyle habits can support kidney health?

General kidney-friendly habits include eating less salt, staying physically active as your healthcare provider advises, not smoking, and keeping follow-up appointments. Avoid NSAID pain relievers such as ibuprofen unless your clinician says they are safe for you, because they can affect kidney function.

Will I need dialysis or a kidney transplant?

Not everyone with IgA nephropathy develops kidney failure. If kidney failure does occur, dialysis and kidney transplant are treatment options. Kidney transplants often do well, although IgA nephropathy can sometimes recur. A nephrologist can help you understand your risk and plan ahead if needed.

What should I ask my nephrologist?

Consider asking about your current kidney function, blood pressure goal, urine protein level and target, medication options, possible side effects, monitoring schedule, and whether newer treatments may fit your situation. Bringing questions and test results to appointments can make conversations easier.

Where can I find education and support?

TLHF offers a free IgA Nephropathy Guide and a supportive chapter community. The IgA Nephropathy Foundation is another condition-specific resource. Educational resources do not replace individualized medical advice, so discuss any changes to treatment, diet, or medications with your healthcare provider.

Take your next informed step

Download the free IgA Nephropathy Guide from The Liver Hope Foundation. Use it to prepare questions for your nephrologist about blood pressure and urine protein targets, kidney-protective habits, and newer treatment options. You do not have to navigate a diagnosis alone.